Best Dewormer for Puppies – 2025 Reviews

I was genuinely impressed by how comprehensive this dewormer is—it covers the most common worms puppies encounter, and the chewable format means no struggling to get it down. Users consistently report seeing dead worms passed within 1-3 days, and many mentioned it saved them expensive vet visits. The fact that you can give it with or without food makes dosing incredibly convenient, especially for puppies with sensitive stomachs.

A small number of users noted that some puppies might experience mild diarrhea or vomiting, though this typically resolves quickly.

If you need a reliable, broad-spectrum dewormer that puppies actually enjoy taking, this is your top choice.

What stands out with Panacur is its proven track record and affordability—it’s been around for years and has a loyal following because it simply works. The powder form mixes easily into wet food, and I’ve found that even picky eaters don’t notice it. Users love that there are typically no side effects, and many use it routinely as a preventive measure.

Since it’s a powder, it can be messy if not mixed properly, and some users wish it came in a chewable form for easier administration.

For an effective, no-fuss dewormer that won’t break the bank, Panacur C delivers outstanding value.

The biggest advantage here is the age suitability—being able to deworm puppies at 2 weeks is crucial for breeders and rescuers. The liquid is sweet like honey, so most puppies lap it up without issue, and users report seeing worms expelled within 24 hours. It’s also incredibly cost-effective compared to vet visits.

Some users mentioned that their pets disliked the taste or experienced mild diarrhea, though this is less common.

If you have very young puppies or need a cost-effective liquid option, this is the best budget-friendly choice.

I love how comprehensive and convenient this dewormer is—the chewables are often eaten like treats, and the 7-way coverage means you’re protected against most common threats. Users consistently mention rapid results, often within one dose, and the value per tablet is excellent compared to single-use options.

A few users reported that their dogs experienced vomiting or diarrhea, so it’s wise to monitor your puppy after the first dose.

For small puppies needing broad protection in an easy-to-give format, this is an excellent choice.

The broad coverage and early age suitability make this a standout—it’s rare to find a dewormer that handles whipworms along with the usual suspects. The chewable form is convenient, and many users note that their dogs eat it eagerly, with visible results in just one dose.

Some users find the tablets too hard for small puppies to chew easily, and a few reported no improvement in their dog’s condition.

If you need reliable, all-in-one protection for puppies over 4 weeks, Elanco delivers excellent performance.

I appreciate the value and effectiveness of this dewormer—the 12-tablet pack lasts through multiple treatments, and users report that even picky eaters take it willingly. It’s particularly good for tapeworms and pinworms, with many seeing bloated bellies improve within days.

A few users mentioned that the tablets crumble easily, making dosing messy for very small puppies.

For affordable, multi-strain protection in a chewable form, this is a very reliable option.

The ease of use is fantastic here—the liquid mixes easily into food, and the sweet taste means most puppies accept it without a fight. Users love that it starts working in as little as 3 hours, and it’s a great alternative to prescription options.

Some users reported vomiting or diarrhea in their pets, and it only covers two types of worms, so it’s less comprehensive than others.

If you need a fast-acting liquid dewormer for hookworms and roundworms, this is a solid choice.

For a budget-friendly option that doesn’t compromise on effectiveness, this dewormer surprises many users—it’s often compared to Panacur but at a lower cost. The powder is easy to dose, and I’ve seen it work well for puppies with no side effects.

Since it’s a generic, some users are cautious about consistency, and the packaging isn’t as robust as branded products.

If you’re on a tight budget but want reliable deworming, this is a trustworthy generic choice.

This dewormer covers a wide range of worms and is perfect if you have a larger puppy or anticipate your pup growing into a big dog. The chewables are generally well-accepted, and users report effectiveness after just one dose.

Some users noted issues with diarrhea and vomiting, and it’s less suitable for very small puppies under 25 lbs.

For larger puppies or those who will grow into big dogs, this offers comprehensive protection in an easy format.

If you’re dealing specifically with roundworms, this dewormer does the job well—it’s fast-acting, and users note that pets show no issues taking it when mixed with food. The large 12-oz bottle offers good value for multiple doses.

The limited spectrum means it’s not suitable for other worms, and some pets dislike the taste, making administration tricky.

For targeted roundworm treatment in puppies over 6 weeks, this is an effective option, but you’ll need additional products for broader protection.